News

June 2024

3rd June 2024: 1.5 million interactions available curated to the IMEx Consortium standards

As of 3rd June 2024, more than 1.5 million molecular interactions are available for search and download from the IMEx website and from Consortium member websites. Curated to IMEx standard, it includes information on binding sites, the effect of point mutations on interactions, as well as contextual information such cell lines and any agonist/antagonist treatment, when available.

December 2023

11th December 2023: IMEx Consortium achieves Global Biodata Coalition core resource status members

The IMEx Consortium has been selected as one of a limited collection of data resources recognised as critical to life science and biomedical research worldwide. More here (https://globalbiodata.org/global-biodata-coalition-announces-outcome-of-2023-global-core-biodata-resource-selection-process/)

July 2023

13th July 2023: Latest release of IMEx data via IntAct website

https://www.ebi.ac.uk/about/news/updates-from-data-resources/intact-244-complex-portal-244/

June 2023

27th June 2023: IMEx data used to identify groups of traits likely to share an underlying genetic and biological process and modules linked to human diseases

Barrio-Hernandez I, et al. Network expansion of genetic associations defines a pleiotropy map of human cell biology. Nat Genet. 2023 Mar;55(3) 389-398. doi:10.1038/s41588-023-01327-9. PMID: 36823319

24th June 2023: IMEx data used to explore miRNA Interactions

Panni et al. The landscape of microRNA interactions annotation: analysis of three rare disorders as case study https://europepmc.org/article/PPR/PPR679890

20th June 2023: IMEx data available via Human Protein Atlas website

https://www.proteinatlas.org/news/2023-06-19/the-version-23-of-the-human-protein-atlas-with-updated-genome-assembly-and-a-new-interaction-section

13th June 2023: Find out how the UniProt Knowledgebase uses IMEx data in their latest publication

https://www.mcponline.org/article/S1535-9476(23)00102-0/fulltext

April 2023

25th April 2023: Biocuration conference 2023

Simona Panni introduces the landscape of microRNA interactions annotation in IMEx by highlighting the analysis of three rare disorders as a case study, Kalpana Panneerselvam described the IMEx Consortium’s contextual metadata and tissue-specific interactomes